Pharmacogenetics (PGx)
A medication that helps one person may be ineffective for another, or in the worst case, cause severe side effects. The field of pharmacogenetics investigates genetic variants that influence drug response. Determining a patient’s individual genotype enables personalized therapy recommendations.
What is Pharmacogenetics?
Pharmacogenetics is the science that examines how genetic differences influence the effect of medications. It helps to understand why some people respond better to certain drugs than others, or why side effects vary in severity. By analyzing individual genetic characteristics, tailored treatment plans can be developed to increase medication efficacy and reduce the risk of undesirable effects.
What are the benefits of the analysis?
Personalized Medication
Optimal selection and dosage of medications
Avoidance of Side Effects
Reduces the risk of severe, undesirable effects
Improved Efficacy
Higher success rate in treatment
Which active ingredients are covered by the analysis?
You can find an overview of all active ingredients and medications covered by our PGx screening here.
Are the recommendations based on official guidelines?
Yes, various consortia worldwide publish official pharmacogenetic recommendations. Among the most significant are the Dutch Pharmacogenetics Working Group (DPWG), the Clinical Pharmacogenetics Implementation Consortium (CPIC), and the U.S. Food and Drug Administration (FDA). These organizations develop evidence-based guidelines for the clinical use of pharmacogenetics and form the basis for personalized drug therapy. They provide concrete recommendations for adjusting medication dosages based on genetic information to maximize efficacy and ensure safety.