Dental disorders

Dental disorders such as tooth agenesis and oligodontia affect the development and number of teeth, where individual teeth are missing or never formed. Amelogenesis imperfecta (AI) is a genetic disorder that affects the formation of tooth enamel, leading to abnormal tooth structure and color.

Request Test

  • Sample material: EDTA whole blood
  • Testing method: Next-Generation Sequencing (NGS) (if applicable, Sanger sequencing, MLPA, molecular diagnostics via PCR)
  • Turnaround time: from 2 weeks
  • Required documents:

Detailed information on sample submission can be found here.

DIAGNOSTIC SERVICES

The following table presents our indication-specific range of examinations in this field:

INDICATION ANALYSIS
Amelogenesis imperfecta (AI) Gene panel
Tooth agenesis, oligodontia Gene panel

The genes examined in the respective gene panels are always based on the current versions of the Genomics England PanelApp, the PanelApp Australia, the OMIM Phenotypic Series, and the entries from GeneReviews.

If the suspected diagnosis or indication is not listed here, or if it involves a complex syndromic clinical picture, it is possible to request exome sequencing based on phenotypic characteristics.

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